Workshop

European Molecular Biology Organization

 

HISTONE VARIANTS &

GENOME REGULATION

12 - 14 October| 2011 | IGBMC | Strasbourg | France

Programme

 

Download Programme: (word.doc)

 

Day 1 (12th october)

 

8:30 - 09:55 Registration

1) Structure of histone variants and mode of incorporation to the chromatin

  Chair: Patrick Schultz
09:55 - 10:00 Introduction

10:00 – 10:45

Pierre Chambon (Opening Lecture)

10:45 – 11:15

Karl Ekwall

CENP-A and H2A.Z targeting mechanisms in fission yeast

11:15 – 11:45

Karolin Luger

The effects of histone variants on chromatin structure and dynamics

11:45 – 12:15

Coffee Break

12:15 - 12:30

Short Talk : Yuda Fang
Four amino acids guide the assembly or disassembly of Arabidopsis histone H3.3-containing nucleosomes

12:30 - 13:00

Peter Lewis
Varying the chromatin landscape with histone H3.3

13:00 - 13:15

Short Talk: Kristina Lakomek

remodelling complex and its actin-related protein (Arp) subunits - a putative link between chromatin remodelling and actin metabolism

13:15-16:00

Lunch / Poster session

  Chair: Bill Kelly

16:00-16:30

Genevieve Almouzni
Epigenetic challenges in centromere inheritance during the cell cycle

16:30-17:00

Bing Zhu       
H3.3-H4 tetramer splitting events feature cell-type specific enhancers

17:00-17:15

Short Talk: Sandra Hake
H2A.Z-2.2 is a novel alternatively spliced histone H2A.Z variant that causes significant nucleosome destabilization

17:15 – 17:45

Coffee Break

17:45 – 18:15

David John Tremethick
A unique H2A histone variant occupies the transcriptional start site of active genes

18:15 – 18:30

Short Talk: Olivier Binda
Lysine methylation of the histone H2A variant H2AZ by SETD6

18:30 – 19:00

Panel Discussion

19:00

Dinner

Day 2 (13th october)

 

2) Genome organization

  Chair: Evi Soutoglou

9:00 – 9 :30

Daniela Rhodes
Chromatin structure and recognition

9:30 – 10 :00

Rob Schneider
Linker histone H1 variants and their function

10:00 – 10:30

Steve Henikoff
Characterization of centromeric nucleosomes in vivo

10:30 – 11:00

Coffe break

11:00 – 11:15

Short Talk: Patrizia Filetici
Gcn5 and Ubp8 mediate the turnover of histone  variant Cse4 and regulate the centromeric nucleosome

11:15- 11:45

Simon Chan
Centromere competition: a sensitive assay for CENH3 function

11:45-12:00

Short Talk: Patrick Heun
Drosophila CENH3 is sufficient for centromere formation

12:00 – 12:15

Ramesh Yelagandula
A novel class of histone H2A variants in Arabidopsisthaliana

12:15 – 14:00

Lunch

3) Responses to the environment

  Chair: Fred Berger

14:00 -14:20

Caroline Dean
Do histone variants play a role in vernalization?

14 :20-14 :35

Short talk: Bas Rutjens
VRN1-Mediated Nucleosome Homeostasis Orchestrates Arabidopsis Genome Regulation

14 :35-15:05

Philip Wigge

The role of H2A.Z-nucleosomes in mediating temperature sensing in plants

15:05-15:35

Coffee Break

15:35-15:50

Short Talk: Niraj Lodhi
Genome wide analysis of PARP1 in chromatin

15:50-16:20

George A.M. Cross
Doing things differently: transcription and histone variants in trypanosomes

16:20-16:35

Short Talk: Michael Duffy
P. falciparum histone variant PfH2AZ associates with the apicomplexan histone variant H2BV and is dynamically regulated at transcribed virulence gene promoters

16:35 –17:00

Panel Discussion

 

Free Evening

Day 3 (14th october)

 

4) Reprogramming and stem cells

  Chair: Maria Elena Torres-Padilla

 9:00 – 9:50

John Gurdon (Keynote)

Chromosomal proteins and nuclear reprogramming

10:00 – 10:30

Petra Hajkova
Molecular mechanisms of epigenetic reprogramming in mouse development

10:30 – 11:00

Coffee break

11:00 – 11:15

Ana Boskovic
Dynamics of histone variants and modifications in early mammalian embryogenesis

11:15 – 11:30

Short Talk: Marcus Buschbeck
MacroH2A regulates lineage-commitment in embryonic stem cells

11:30 – 12:00

Andreas Ladurner
Histone-variant related macrodomains mediate NAD metabolite-dependent nuclear dynamics

12:00-15:00

Lunch and Poster session

5) Gametogenesis and reproduction

  Chair: Genevieve Almouzni

15:00-15:30

Ben Loppin
Yemanuclein, the Drosophila ortholog of Human UBN1, associates with HIRA for the deposition of H3.3 nucleosomes in the male pronucleus

15:30- 16-00

Bill Kelly
Histone Dynamics During Germline Development in C. elegans

16:00 – 16:15

Short Talk: David Michod
H3.3 loading upon neuronal activation: role of the histone chaperone DAXX

16:15 – 16:45

Coffee Break

16:45 – 17:15

Saadi Khochbin

Post-meiotic male genome reprogramming directed by histone variants

17:15 – 17:45

Fugaku Aoki
Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells

17:45 – 18:15

Kami Ahmad
Histone H3.3 deposition in a model system of gene induction.

18 :15

General discussion / Concluding remarks

19 :00

Dinner  /    Party

   

 

 

 

 


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