Programme

5 May | 6 May | 7 May | 8 May | 9 May | Poster Session 1 | Poster Session 2 | Poster Session 3

 

Sunday, 5 May


 

16.00-18.00

Registration (deck 5)

 

18.00

Welcome - Anne Simonsen

 

Keynote address and opening lecture
Patrice Codogno (session chair)

 

18:10-19:00

Per O Seglen (Norway) - "Use of inhibitors and cargo assays to dissect autophagic-lysosomal pathways: An autophagobiography"

 

19:00-19:30

Yoshinori Ohsumi (Japan) - “Novel Atg proteins in yeast”

 

19:30

Dinner and Welcome reception (Panorama deck 8)

 

20:00

Departure Bergen

 

20:30

Dinner

 

 

 

Monday, 6 May


 

Regulators of autophagy
Sharon Tooze (session chair)

 

09:00-09:30

Dan Klionsky (USA) - “The mechanism and regulation of macroautophagy” 

 

09:30-10:00

Adi Kimchi (Israel) - “Signaling pathways regulating autophagy”

 

10:00-10:20

Carine Joffre (France) - “Ral GTPases together with NDR kinases control the switch between autophagy and apoptosis”

 

10:20-11:00

Coffee break

 

11:00-11:30

Beth Levine (USA) - “Links between EGFR Signaling, Beclin 1, and Lung Cancer"

 

11.30-12:00

Thomas Neufeld (USA) - “Autophagy regulation by nutrient and hormonal signaling pathways”

 

12:00-12.20

Tor Erik Rusten (Norway) - “Two-tiered control of epithelial growth and autophagy by the insulin receptor and the Ret-like receptor, Stitcher”

 

12.20-12:40

Kim D. Finley (USA) - “Changes in Autophagic Function, Insulin Signaling and Diet In Drosophila Suppresses the Age-Related Decline of Neural Function and Behaviors”

 

13.00-15.00

Lunch plus free time (Geiranger)

 

Regulators of autophagy (cont.)
Ivan Dikic (session chair)

 

15:00-15:30

Andrea Ballabio (Italy) - "A transcriptional link between cellular clearance and energy metabolism

 

15:30-16:00

Marja Jäättelä (Denmark) - "Control of autophagosome maturation by sphingolipids"

 

16:00-16:20

Carmine Settembre (Italy) - “TFEB co-regulates autophagy and lipid metabolism via the nuclear co-receptor PGC1α”

 

16:20-17:00

Coffee break

 

17:00-17:30

Ana Maria Cuervo (USA) - "Chaperone-mediated autophagy in quality control and cellular metabolism" 

 

17:30-18:00

Patrice Codogno (France) - "Autophagy and cell polarity"

 

18:00-18:20

Sophie Pattingre (France) - "Regulation of autophagy by acetylation"

 

18:20-20:10

Poster session I – poster # 1-37

 

20.30

Dinner

 

 

 

Tuesday, 7 May


 

06:00-12:00

Ship in Trondheim

 

07:00-9:00

Breakfast

 

Autophagosome biogenesis
Zuvlun Elazar (session chair)

 

09:00-09:30

Tamotsu Yoshimori (Japan) - "Insights in to membrane dynamics in autophagy"

 

09:30-10:00

Noboru Mizushima (Japan) - "Autophagosome formation and maturation"

 

10:00-10:30

Claudine Kraft (Austria) - "Role and function of the Atg1 kinase in autophagy"

 

10:30-11:15

Coffee break

 

11:15-11:45

Eeva-Liisa Eskelinen (Finland) - “Visualizing autophagosome biogenesis at high resolution”

 

11.45-12.05

Hannah Dooley (UK) - “Investigating the function of WIPI2 – Atg16L1 interaction in starvation induced autophagy initiation”

 

12.05-12.25

Gian Maria Fimia (Italy) - “Regulation of autophagy by the E3 ubiquitin ligase Cullin 4”

 

13.00

Lunch and free time

 

Autophagosome biogenesis (cont.)
Terje Johansen (session chair)

 

15:00-15:30

David Rubinsztein (UK) - “Regulation of early steps in autophagosome biogenesis”

 

15:30-16:00

Fulvio Reggiori (the Netherlands) - “Autophagosome biogenesis in yeast”

 

16:00-16:30

Coffee (ship go through “Stokksundet”)

 

16:30-17.00

Nick Ksistakis (UK) - “Regulation of autophagy by PI3P and calcium”

 

17:00-17:30

Sascha Martens (Austria) - “Autophagosome biogenesis: Insights from reconstitution” Supported by the COB

 

17:30-18:00

Li Yu (China) - "Autophagic lysosome reformation"

 

18:00-18:30

Meet the editors

 

18:30-20.30

Poster session II – poster # 38-75

 

20.30

Dinner

 

 

 

Wednesday, 8 May


 

07:00-9:00

Breakfast

 

07:00

The ship passes the Artic Circle

 

07:45

The ship passes ”Rødøyløva”

 

09:10

Ship approaching Ørnes

 

Selective types of autophagy
Fulvio Reggiori (session chair)

 

09:00-09:30

Ivan Dikic (Germany) - "Development of specific inhibitors of selective and non-selective autophagy"

 

09:30-10:00

Zuvlun Elazar (Israel) - “Functional differences define the Atg8 family members”  

 

10:00-10:30

Coffee break + Polar circle (activities deck 9)

 

10:30-11:00

Terje Johansen (Norway) - “Cargo adaptors and receptors”

 

11:30-12:00

Felix Randow (UK) - "Autophagy in host-pathogen interactions"

 

12:00-12:20

Laure-Anne Ligeon (France)-“LC3-positive Yersinia-containing vacuoles and SNARE trafficking during invasion”

 

12:20-12:40

Jon Lane (UK) - “Active mitochondria avoid mitophagy through coordinated regulation of mitochondrial fusion and fission pathways”

 

12.15-15.00

Lunch and free time

 

 

 

 

Vps34, PI3P and autophagy
Harald Stenmark (session chair)

 

15:00-15:30

Gilbert Di Paolo (USA) - "The role of Vps34-independent PI3P sources in autophagy"

 

15:30-16:00

Roswitha Krick (Germany) - "Structural and functional characterization of PROPPINs" Supported by the COB

 

16:00-16:45

Coffee break (16:00 ship passes ”Landegode fyr”)

 

16:45-17:15

Tassula Proikas-Cezanne (Germany) - "Differential functions of human WIPI proteins in phagophore formation"

 

17:30-17:45

ship passes “Lofotveggen”

 

17:45-19:45

Poster session III – poster # 76-109

 

20:30

Dinner

 

21:00-22:00

ship in Svolvær – “the capital of Lofoten”

 

23:00

sailing through “Raftsundet” and “Trollfjorden” (a must see; activities at deck 9)

 

 

 

Thursday, 9 May


 

Autophagy and disease
David Rubinsztein (session chair)

 

09:00-09:30

Vojo Deretic - "A  specialized lipid platform for assembly of autophagic machinery: lessons from immunity"

 

09:30-10:00

Francesco Cecconi (Italy) - "Roles of Ambra1 and autophagy in regulatory T cells differentiation"

 

10:00-10:30

Anna Katharina Simon (UK) - "Autophagy in hematopoeisis, stem cells and AML"

 

10:30-11:00

Coffee break

 

11:00-11:20

Maria L. Torgersen (Norway) - “Targeting autophagy potentiates the apoptotic effect of the histone deacetylase inhibitor valproic acid in t(8;21) AML cells”

 

11:20-11:40

Simone Cenci (Italy) - “Plasma cells require autophagy for sustainable immunoglobulin production”

 

11.30-12.00

Ai Yamamoto (USA) - "Alfy and the brain"

 

12:10-12:15

Conference closing (Anne Simonsen)

 

Check-out

 

12.30

Lunch plus free time

 

14.30

Arrival Tromsø

 

 

Poster session

Poster board size: 100 cm wide x 204 cm high.

 

Poster session I (Monday 18:20 - 20:10)
  Presenter  
Poster # Last name First name Abstract title
1 Abeliovich Hagai A role for mitochondrial dynamics in segregating mitochondrial matrix proteins during stationary phase mitophagy
2 Anwar Tahira Localization of Beclin 1 and its effects on autophagosome formation
3 Arama Eli Unique Atg8-positive organelles, the ubiquitin-p62 pathway and autophagy mediate paternal mitochondrial destruction after fertilization in Drosophila
4 b'chir wafa The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
5 Bader Christie Investigating the function of autophagy related proteins in Drosophila
6 Bakke Oddmund Imaging the early endosomal pathway: Opening of the fusion pore and how  fusion of early endosomes induces molecular motor-driven tubule formation and fission.
7 Bakula Daniela Towards the identification of the WIPI interactome
8 BEAU Isabelle SQSTM1/p62 is a new player in the epithelial-mesenchymal transition
9 Bell Emily A role for autophagy in Met receptor tyrosine kinase regulation.
10 Birgisdottir Åsa Birna Components of the class III phosphatidylinositol 3-kinase (PI3KC3) complex interact with ATG8 family proteins via LIR motifs
11 Blomhoff Heidi Kiil Can retinoic acid stimulate B cell functions via induced autophagy?
12 Boada-Romero Emilio TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3
13 Bouhy Delphine Autophagy deficits: potential common pathomechanisms leading to peripheral neuropathy?
14 Brech Andreas Unravelling the functional role of p62 in cargo delivery during selective autophagy
15 Burnett Sarah Unexpected Phosphoregulation of Peroxisome Degradation by Pex3
16 Carlsson Sven Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
17 Chagin Andrei Inhibition of autophagy-lysosomal pathway promotes size of chondrocytes in Atg5-independent manner.
18 Cianfanelli Valentina Ambra1: a pro-autophagic factor regulating cell proliferation and tumorigenesis
19 Ciuffa Rodolfo Cryo-EM structure of p62
20 Clarke Alex Autophagy is increased in human and murine SLE B lymphocytes and is required for the development of plasma cells
21 Deng Yizhen Dual function of Magnaporthe oryzae sorting nexin 41: protein sorting and pexophagy
22 Devereaux Kelly Regulation of mammalian autophagy by Class II and III PI 3-kinases through PI3P synthesis
23 Di Bartolomeo Sabrina BECLIN1-COFACTOR AMBRA1 IS POST-TRANSLATIONAL MODIFIED DURING CELL CYCLE PROGRESSION
24 Di Malta Chiara Astrocyte autophagy dysfunction triggers neurodegeneration in a lysosomal storage disorder
25 Ding Wen-Xing Loss of Atg5 in the Mouse Liver Leads to Inflammation, Fibrosis and Liver Tumorigenesis
26 Dooley Hannah Investigating the function of WIPI2 – Atg16L1 interaction in starvation induced autophagy initiation
27 Elgendy Mohamed Reciprocal Regulation Between Mcl-1 and Beclin 1 Contributes to Their Functional Counteraction in Tumorigenesis
28 Engedal Nikolai Mobilizers of intracellular calcium potently block autophagy
29 enserink jorrit TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy
30 Fahmy Ahmed The recruitment of autophagy elongation complex (ATG5-12/16) at the Hepatitis C virus replication site is required for efficient viral replication.
31 Feichtinger Sabine Human cytomegalovirus modulates the autophagy-initiating protein kinase Ulk1 for an efficient replication cycle
32 Færgeman Nils Functional autophagy is required to maintain viability of Saccharomyces cerevisiae during perturbation of fatty acid metabolism
33 Ganley Ian mTOR Regulation of the VPS34 lipid kinase

 

Poster session II (Tuesday 18:30 - 20:30)
  Presenter  
Poster # Last name First name Abstract title
34 Gassen Nils The Hsp90 cochaperone FKBP51 Impacts Autophagy and Protein Kinases relevant to Psychiatric Diseases
35 Gatti Evelina Autophagy inhibition promotes defective neo-synthesized proteins storage in ALIS, and induces proteasome processing and MHCI-restricted presentation.
36 Grumati Paolo Autophagy thwarts skeletal muscle homeostasis and muscular dystrophies
37 Hagen Linda Korseberg 3MA-Sensitive PI3K is Required both for LC3 Lipidation and for Subsequent Autophagic Sequestration
38 Hamasaki Maho Autophagosomes form at ER−mitochondria contact sites
39 Hansen Malene Role of autophagy in C. elegans aging
40 Harvald Eva Quantitative Proteomics Uncovers Novel Regulators of Autophagy and Aging in C. elegans
41 Hill James An autophagic role in Alzheimer's disease for intermittent dietary periods of very low-protein, high-carbohydrate intake
42 Isakson Pauline TRAF6 mediated ubiquitination is required for midbody ring degradation by selective autophagy
43 Jenny Andreas Functional assessment of Chaperone Mediated Autophagy in Drosophila.
44 Jimenez Sanchez Maria Regulation of autophagy by the Hedgehog signalling pathway
45 JOFFRE Carine Ral GTPases together with NDR kinases control the switch between autophagy and apoptosis
46 Johansson Ida The omega-3 polyunsaturated marine lipid DHA induces autophagic flux in normal epithelial ARPE-19 cells but inhibits growth of colon cancer cells with low basal autophagy
47 Juhasz Gabor Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal health in Drosophila
48 Kabuta Tomohiro Direct Uptake and Degradation of RNA by Lysosomes
49 Karanasios Eleftherios Omegasomes and the ULK1 complex.
50 Katheder Nadja TNF-mediated tumor suppression and autophagy
51 Kim Deok Ryong The autophagic process is negatively regulated by combination of p18 and RKIP via modulation of interaction with LC3 upon deprivation
52 Knizhnik Anna Temozolomide induces autophagy in glioma cells which inhibits apoptosis and stimulates senescence
53 Lamb Christopher TBC1D14 and the TRAPP complex in mammalian macroautophagy
54 Lane Jon Active mitochondria avoid mitophagy through coordinated regulation of mitochondrial fusion and fission pathways
55 Lebeau Justine p58IPK-mediated attenuation of the pro-apoptotic PERK-CHOP pathway allows malignant progression upon low glucose
56 Li Guo Hua Autophagy induced by iron-overload contributes to diastolic cardiomyopathy
57 LIU LIANGFENG Over expression of alpha-synuclein impairs the nuclear translocation of TFEB
58 lu jiahong NRBF2, a novel PI3K-III complex component, regulates autophagy at induction and maturation stages.
59 Lussignol Marion A viral protein represses autophagy by interacting with the protein kinase PKR
60 Macintosh Robin Autophagy may promote cancer cell invasion through cell autonomous and non-autonomous mechanisms
61 Mannack Lilith Functional Interplay of ATG4 with ATG8 in Mammalian Autophagosome Biogenesis
62 Martinez-Vicente Marta Bax channel activity mediates lysosomal membrane permeabilization linked to Parkinson's disease
63 Mauvezin Caroline Role of the proton pump V-ATPase in autophagy
64 Menzies Fiona Identification of Hedgehog transcriptional targets that may regulate Autophagy
65 Minina Elena A. The role of autophagy in the regulation of plant phenology and longevity
66 Mukadam Aamir Analysis of the interaction between the mammalian GTPase GIMAP6 and an autophagy gene 8 homologue

 

Poster session III (Wednesday 17:45 - 19:45)
  Presenter  
Poster # Last name First name Abstract title
67 Nezis Ioannis Towards the identification of novel selective autophagy receptors in Drosophila melanogaster
68 Nicot Anne-Sophie GSK3 regulates protein aggregation in muscle through phosphorylation of the autophagic receptor NBR1
69 Overbye Anders Colocalization of Immunoblotted LC3-I with a Cross-stained Nucleoside Diphosphate Kinase
70 Pankiv Serhiy Nucleocytoplasmic shuttling of Alfy: characterization of signals involved and its regulation.
71 Pardo Raul Regulation of neuronal autophagy by the Fat/Hippo pathway
72 Patrice X. PETIT Cross-talk betwwen apoptosis and autophagy: mechanistic issues  of the cell death signal transduction induced by curcumin  associated with the ER-stress and the mitochondrial-dependant  pathway
73 Pause Arnim A conserved metabolic pathway regulating AMPK-ULK-dependent autophagy and metabolic stress survival
74 Pettersen Kristine A role of autophagy in cancer cachexia
75 pierre philippe Microbial detection and IL-4 controls autophagy and subsequent endogenous MHC II-restricted presentation in dendritic cells.
76 Putyrski Mateusz Modulation of autophagy by engineered protein variants
77 Rein Theo Autophagy in stress-related psychiatric diseases: evidence from antidepressant and cochaperone action
78 Romagnoli Alessandra Regulation of Pink1/Parkin-mediated mitophagy by Ambra1
79 Rotondo Sergio Engagement of the immune system GTPase GIMAP6 with the autophagic pathway
80 Rubinstein Assaf Atg12 Promotes Mitochondrial Apoptosis via Interaction with Bcl-2 Family Proteins, and is Phosphorylated by p38 MAPk
81 Sachse Carsten Cryo-EM structure of p62
82 Saetre Frank Lipidation, Turnover and Recycling of LC3 during Autophagy in Isolated Rat Hepatocytes
83 Schaaf Marco ULK1 promotes hypoxia-induced autophagy
84 Sebti Salwa Bat3 : a new modulator in the regulation of autophagy
85 Shen Han-Ming A novel inhibitory effect of mTORC1 on autophagy via suppression of lysosomal function
86 SIROHI KAPIL M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells
87 Sjøttem Eva The stress induced microRNAs mir-7 and mir-106b regulate p62/SQSTM1 and multiple proteins in the autophagy pathway
88 SONG JUXIAN Alpha-synuclein overexpression inhibits HMGB1-mediated autophagy: Prevention by Corynoxine B
89 Szatmari Zsuzsanna Rab11 plays role in the maturation of autophagosomes and endosomes as a negative regulator of Hook
90 Vaccari Thomas The SNARE protein Snap29, which is compromised in CEDNIK syndrome, is a novel  regulator of Autophagosome maturation.
91 Vaccaro Maria The VMP1-Beclin 1 interaction regulates Autophagy induction
92 Villamil Ortiz Javier Gustavo COMPARATIVE STUDY OF THE ROLE OF THE GENERATED AUTOPHAGY IN TAUOPATHY IN ALZHEIMER'S DISEASE (AD) AND CEREBRAL ISCHEMIA (CI)
93 Walczak Marta Roles of Atg12-Atg5/Atg16 during autophagosome formation
94 Wang Ling SIRT3 Deacetylates FOXO3 to Induce Mitophagy in Endothelial Cells under Oxidative Stress
95 Wollert Thomas Autophagocytic Coat Assembly and Disassembly
96 Wong Esther Molecular Determinants of Selective Clearance of Protein Inclusions by Autophagy
97 Wu Yaowen Synthesis of Lipidated LC3 Protein
98 Ylä-Anttila Päivi Rab24 facilitates autophagosome clearance
99 ZOIS CHRISTOS Autophagy in breast cancer in normoxia and hypoxia: distinct characteristics between HER2 positive and HER2 negative cell lines and tumors.