The first day of the Workshop will be held in the Aula Magna del Rettorato dell'Università degli Studi di Torino, via Po 17, Torino


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While the following days will be at: IRCC, Candiolo


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Thursday, March 7 | Aula Magna del Rettorato dell'Università degli Studi di Torino,via Po 17, Torino

14:00

Registration

15:30

Opening of the Workshop

16:00

Key Lecture: Marino Zerial (MPI for Molecular Cell Biology and Genetics, Dresden)
Multi-scale analysis of endosome biogenesis, cell polarity and metabolism in mouse liver

             

Session I: From single-cell to multicellular dynamics 

16:50

Keith Mostov (University of California, San Francisco)

Regulation of epithelial apical polarity orientation by phosphorylation of the Podocalyxin complex

17:25

Frank Jülicher (MPI for the Physics of Complex Systems, Dresden)

Dynamic organization of epithelia

18:00

"Apericena" (Finger Food & Wine)

19:30 - 21:00

Guided tour of Torino city center

   

Friday, March 8 | IRCC, Candiolo

         

Session II: From single-cell to multicellular dynamics

9:35

Carl-Philipp Heisenberg (Institute of Science and Technology, Austria)
Cell and tissue mechanics in zebrafish gastrulation

10:10

Adele Khavari (Chalmers University of Technology, Gothenburg)

Tumor growth and metastasis is driven by microenvironment mechanics

10:30

Coffee Break

11:00

Matt Gibson (Stowers Institute for Medical Research, Kansas City)

Coordinating mitosis and morphogenesis in proliferating epithelia

11:35

Oscar Ocaña (Instituto de Neurociencias CSIC-­UMH, San Juan de Alicante)

Prrx1, a novel class of EMT inducer in embryos and cancer cells

11:55

Marta Shahbazi (National Cancer Research Centre, Madrid)

Microtubule targeting to Adherens Junctions via the novel CLASP2-­p120 interaction

12:30

Lunch

13:30

Poster Session & Coffee

            

Session III: Cell polarity in migration

14:30

Carole Parent (National Cancer Institute, Bethesda)

Live imaging of signal relay during chemotaxis and its relevance to inflammation

15:05

Martin Meier-Schellersheim (NIAID, Bethesda)

Mechanisms of chemoattractant-induced cell polarization and adaptation: a combined theoretical and experimental approach

15:40

Gema Malet (IFOM, Milan)

Collective migration overcomes endocytosis-­dependent reversal of chemotactic direction in CLL leukemic cells

16:00

Coffee Break

16:30

Günther Gerisch (Max Planck Institute for Biochemistry, Martinsried)

Oscillating front-tail transitions visualized by PIP3-PTEN patterns and actin waves

17:05

Igor Weber (Ruđer Bošković Institute, Zagreb)

A dual role model for Rac1 and DGAP1 in cell migration

17:25

Tim Elston (University of North Carolina,Chapel Hill)

Mathematical models of cell polarization and migration

18:00

Bus leaving to hotels in Torino

   

Saturday, March 9 | IRCC, Candiolo

              

Session IV: Cell polarity in migration and development

9:00

Emilio Hirsch (Molecular Biotechnology Center, Turin)

The interplay between PI3K and Rac in leukocyte function

09:35

Elena Seiradake (Oxford University)

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

09:55

Wouter-Jan Rappel (University of California, San Diego)

Combining modeling and experiments to understand eukaryotic chemotaxis

10:30

Rhoda Hawkins (University of Sheffield)

Modelling cell motility and polarity in confined environments

10:50

Coffee Break

11:20

Stephan Grill (Max Planck Institute for Molecular Cell Biology, Dresden)

Morphogenetic mechanochemical patterning

11:55

Roland Wedlich-Söldner (MPI for Biochemistry, Martinsried)

A pulsatile actomyosin network organizes the apical cortex of epithelial cells

12:30

Mithila Burute (CEA and CYTOO, Grenoble)

Cell polarity during Epithelial to Mesenchymal transition

12:50

Lunch

13:40

 Poster Session & Coffee

 Session V: Mechanical interactions in tissue growth

14:25

Jean-François Joanny (Institut Curie, Paris)

Growth and instabilities of healthy and cancerous tissues

15:00

Morgan Delarue (Institut Curie, Paris)

Mechanical control of tumor development

15:20

Tomita Vasilica Stirbat (Institut Curie, Paris)

Collective migration of cells: role of substrate rigidity

15:40 Coffee Break

16:10

Nir Gov (Weizmann Institute of Science, Rehovot)

Random cellular motion in tissues and clusters

16:45

Thomas Risler (Institut Curie, Paris)

Undulation instabilities of epithelial tissues

17:05

Jian Liu (National Heart, Lung, and Blood Institute at NIH, Bethesda)

Two actin network structures dictate the traction oscillation within focal adhesion

17:25

Xavier Trepat (Institute for Bioengineering of Catalonia, Barcelona)

Integrating cell-cell and cell-matrix adhesion forces during collective cell migration

18:00 Bus leaving to Mole Antonelliana (weather permitting)

21:00

Gala Dinner

   

Sunday, March 10 | IRCC, Candiolo

             

 Session VI: Dynamics of cancer from tumorigenesis to metastasis

 

Coffee available during session

08:45

Peter Friedl (NCMLS, Nijmegen)

Cell migration in 3D tissue in vitro and in vivo: principles of guidance and physical limits

09:20

Pascal Silberzan (Institut Curie, Paris)

Collective migration of epithelial cells

09:55

Denis Wirtz (John Hopkins University, Baltimore)

Cancer cell migration in 3D

10:30 Workshop conclusion

11:00

Bus leaving to Turin airport/hotels