Programme

 

Talk length is 15 min plus 7 min discussion

Poster dimensions are 120 x 90 cm (height x width)

 

Saturday, September 14, 2013


16:30 – 18:00

Arrival / Registration

Session I: Entry into meiosis, regulation of meiotic gene expression
Chair: Paula Cohen

18:00

Tim Schedl • St. Louis, USA
Control of the decision to initiate meiotic development in C.elegans

18:22

Christian Eckmann • Dresden, Germany
GLD-4, a cytoplasmic poly(A)polymerase, is part of a translational feedback loop regulating stem cell pool size and meiotic entry in the adult
C. elegans germ line

18:44

Shirleen Soh• Cambridge, USA
Regulatory logic of the gene expression program of meiotic initiation in fetal ovarian germ cells

19:06

Marcia Manterola • New York, USA
Uncovering new functions for the mammalian E-type cyclins in regulating chromosome pairing, synaptonemal complex formation, and telomere stability during male meiosis

19:28

Michael Primig • Rennes, France
Regulation and roles of the conserved exoribonuclease Rrp6 and its target non-coding RNAs during mitotic growth and meiotic development

19:50

Xin Li • Worcester, USA
An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes

20:15

Dinner

 
 

Sunday, September 15, 2013


Session II: Recombination initiation
Chair: Raphaël Mercier

09:00

Gerry Smith • Seattle, USA
Meiotic crossover control – from DNA breakage to DNA repair

09:22

Kunihiro Ohta • Tokyo, Japan
Determinants of meiotic recombination hotspots in S. pombe

09:44

Galina Petukhova • Bethesda, USA
Hotspots of recombination inititation in the mouse

10:06

R. Daniel Camerini-Otero • Bethesda, USA
High-resolution personal genome-wide maps of meiotic double-strand breaks in humans

10:30 – 11:00

Coffee break

11:00

Bernard de Massy • Montpellier, France
Initiation of meiotic recombination in mammals

11:22

Scott Keeney • New York, USA
Controlling the number and location of meiotic double-strand breaks in yeast and mouse

11:44

Nancy Hollingsworth• Stony Brook, USA
Down regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double strand breaks

12:06

Douglas Bishop• Chicago, USA
Overlapping Rad51-Dmc1 foci come in well-separated pairs: A symmetric model for meiotic recombination structure

12:30 – 14:30

Lunch break

14:30 – 17:00

Poster session I (even numbers)

Session III: Chromosome movements and structure
Chair: Scott Keeney

17:30

Julie P. Cooper • London, UK
Telomeres regulate meiotic centromere assembly

17:52

Verena Jantsch • Vienna, Austria
Meiotic quality control at the nuclear envelope

18:14

Iva Tolic-Norrelykke • Dresden, Germany
Nuclear movements in meiotic prophase

18:36

Denise Zickler •Orsay, France
E3 ligase Hei10 links meiotic recombinosome development to SC central component formation and cell cycle progression and reveals two-component patterning of crossover sites

18:58

Maria Jasin • New York, USA
Numerical constraints and feedback control of double-strand breaks in mouse meiosis

19:30 – 21:30

Dinner

21:30 – 22:30

Poster Session I continued

 

Monday, September 16, 2013


Session IV: Chromosome structure
Chair: Anne Villeneuve

09:00

Valerie Borde • Paris, France
Chromatin integrity during meiotic DSB repair: involvement of the CAF-1 and HIR histone chaperones

09:22

Eugenio Sanchez-Moran • Birmingham, UK
Integrating chromatin structure and chromosome dynamics during meiosis?

09:44

Nancy Kleckner • Cambridge, USA
Crossover interference

10:06

Amy MacQueen • Middletown, USA
The position, dynamics and functional role of SUMO within budding yeast synaptonemal complex

10:30 – 11:00

Coffee break

11:00

Andrea Pichler • Freiburg, Germany
Ubc9 sumoylation controls SUMO chain formation and governs meiotic synapsis in Saccharomyces cerevisiae

11:22

Christer Höög• Stockholm, Sweden
Sequential structural alterations within the central region of the synaptonemal complex promotes synapsis

11:44

Akira Shinohara• Osaka, Japan
Meiosis-specific cohesion and DDK (Dbf4-dependent Cdc7 kinase)
-dependent regulate chromosome motion and nuclear envelope remodelling during meiosis

12:06

Monica Colaiacovo • Boston, USA
CRA-1-mediated regulation of protein acetylation modulates DSB formation and SC assembly during meiosis

12:30 – 14:00

Lunch break

14:00 – 17:00

Dresden City Tour

Session V: Recombination progression
Chair: Douglas Bishop

18:00

Francesca Cole • Smithville, USA
Comprehensive mapping of meiotic gene conversion in mouse reveals distinct DSB repair mechanisms

18:22

Neil Hunter• Davis, USA
Roles for ubiquitin-like proteins in designating and implementing crossover recombination during mammalian meiosis

18:44

Michael Lichten• Bethesda, USA
Topoisomerase III and Rmi1 regulate recombination intermediate metabolism during budding yeast meiosis

19:06

Jennifer Fung• San Francisco, USA
A role for Mms4 in preventing multiple invasions during meiotic recombination

19:28

Anton Gartner• Dundee, UK
Meiotic holliday junction resolution in C. elegans

20:00

Dinner

 

Tuesday, September 17, 2013


Session VI: Meiotic quality control and feedback mechanisms
Chair: Yoshinori Watanabe

09:00

Valentin Boerner • Cleveland, USA
Two-step activation of the meiotic recombination program via conserved meiotic checkpoint components

09:22

Matthew Neale • Brighton, UK
Positive and negative regulation of meiotic DNA double-strand break formation by the DNA damage checkpoint kinases Mec1(ATR) and Tel1(ATM)

09:44

Attila Tóth • Dresden, Germany
Chromosome axis functions during mammalian meiosis

10:06

Peter Schlögelhofer • Vienna, Austria
Meiotic DSB formation and interference is under control of ATM but not ATR in Arabidopsis thaliana

10:30 – 11:00

Coffee break

11:00

Andreas Hochwagen • New York, USA
Chromosome-autonomous control of meiotic DNA repair signals by the synaptonemal complex

11:22

Anne Villeneuve• Stanford, USA
Quality control and feedback mechanisms coordinate multiple distinct aspects of the C. elegans meiotic program

11:44

Paula Cohen• Ithaca, USA
CNTD1 is essential for the final selection of crossover sites in mammalian meiosis in males and females

12:06

Sunney Xie• Cambridge, USA
to be announced

12:30 – 14:30

Lunch break

14:30 – 17:00

Poster session II (odd numbers)

Session VII: Checkpoints and chromosome segregation
Chair: Willy Baarends

18:00

Abby Dernburg • Berkeley, USA
Feedback control of meiotic progression in C. elegans

18:22

Kevin Corbett • La Jolla, USA
A hierarchical assembly of HORMA-domain proteins controls chromosome-associated events in C. elegans meiosis

18:44

Enrique Martinez-Perez • London, UK
A chromatin-free pool of HORMA-domain protein HTP-1 regulates chromosome axis morphogenesis and meiotic progression to promote homologous synapsis

19:06

James Turner • Mill Hill, UK
Meiotic silencing in mammals

19:28

Katja Wassmann • Paris, France
The SAC proteins BubR1 and Mps1 have essential roles in mouse oocyte meiosis I

20:00 – 21:30

Dinner

21:30 – 22:30

Poster Session II continued

 

Wednesday, September 18, 2013


Session VIII: Chromosome segregation and centromeres
Chair: Denise Zickler

09:00

Wolfgang Zachariae • Martinsried, Germany
Regulation of cohesin cleavage in Meiosis II

09:22

Barbara Meyer • Berkeley, USA
Roles of multiple cohesin complexes in establishing and releasing meiotic sister chromatin cohesion

09:44

Yoshinori Watanabe • Tokyo, Japan
Cohesin Rad21L mediates DSB-independent homolog pairing in mouse spermatocytes

10:06

Rolf Jessberger • Dresden, Germany
Newly identified roles of specific cohesin complexes and of a cohesin regulatory factor in mammalian meiosis

10:30 – 11:00

Coffee break

11:00

Alberto M. Pendas • Salamanca, Spain
Functional analysis of the meiotic cohesins and their kleisins in the mouse

11:22

Roberto Pezza• Oklahoma City, USA
Centromere interactions and meiotic chromosome segregation in mouse meiosis

11:44

Olaf Stemmann• Bayreuth, Germany
An alternatively spliced bifunctional localization signal reprograms human shugoshin1 to protect centrosomal instead of centromeric cohesin

12:06

Mary Herbert• Newcastle, UK
Regulation of chromosome segregation by Plk1 during meiosis I in mouse oocytes

12:30 – 14:30

Lunch break

Session IX: Kinetochores and spindle
Chair: Wolfgang Zachariae

14:30

Eva Hoffmann • Brighton, UK
Meiotic catastrophe: orthogonal, interdependent effects of joint molecules and meiotic spindle dynamics

14:52

Yasushi Hiraoka • Osaka, Japan
Behaviors and structures of neocentromeres during meiosis in fission yeast

15:14

Marko Marjanovic • Barcelona, Spain
Cep63 deficient mice reveal an essential role for the centrosome in male meiosis

15:36

Adele Marston • Edinburgh, UK
Altered composition and biophysical properties of meiosis I kinetochores

16:00 – 16:30

Coffee break

16:30

Raphaël Mercier • Versailles, France
Centromeric cohesion is protected twice at meiosis, by SHUGOSHINS at anaphase I and by PATRONUS, a putative APC/C regulator, at meiosis interkinesis

16:52

Marie-Hélène Verlhac• Paris, France
A soft cortex promotes asymmetric spindle positioning in mouse oocytes

17:14

Jan Ellenberg• Heidelberg, Germany
Visualizing the mechanisms of spindle assembly and chromosome segregation in mammalian oocytes and early embryos

17:45

Business Meeting
Chair: Bernard de Massy

19:30

Gala Dinner

 

Thursday, September 19, 2013


Departure