Recent years have seen a considerable advance in our understanding of autism and related disorders (Fragile X syndrome, Tuberous Sclerosis, Rett). Yet, there are considerable gaps between experimental and clinical observations and there is little conceptual understanding of how and when does the brain deviate from its developmental program. This raises the highly clinically relevant issue of the fate of neuronal ensembles that have not respected their assigned duties and ended misplaced and/or misconnected. To understand and treat autism, we also need to better understand the relations between the family of autistic disorders and disorders with autistic features. In parallel, behavioural approaches have also been suggested to reduce the severity of the disorder and several clinical trials are presently being conducted. This EMBO Conference brings together leading experts from the entire spectrum of this disorder (basic science, clinical science, psychological tests, clinical trials) and particularly the developmental aspects to compare our observations and elaborate a scenario as to the most likely events occurring at early developmental stages and how to treat them.

Topics that will be covered at the conference include:

  • autism and related disorders notably Fragile X syndrome, Tuberous Sclerosis, Rett syndrome
  • brain development and maturation
  • brain imaging
  • mutations, physiological anomalies, anatomical anomalies and electrical signatures of autism
  • signalling cascades in developmental disorders
  • properties of children with autism and parent interventions
  • clinical evaluation and treatment of autism and related disorders
  • animal models of autism and behavioural aspects





Eden Théâtre,

Boulevard Georges Clémenceau,

13600 La Ciotat


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