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iCLIP: Genomic views of protein-RNA interactions

15 – 21 November 2015 | Mainz, Germany

Image credit: Heng-Chang Chen
 

About the practical course

Throughout its life cycle, each RNA will interact dynamically with numerous RNA-binding proteins (RBPs) that determine how the RNA is processed, where it is localized, whether it is translated and finally how it is degraded. In turn, RBPs can interact with hundreds to thousands of cellular RNAs by recognizing certain sequence motifs or structural elements. Understanding these interactions in a genome-wide manner is crucial for gaining a complete picture of an RBP’s specificity and function.

Individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) has established itself as a leading method to map the RNA interaction sites of a single RBP-of-interest with high resolution and in a quantitative manner. The major objective of this EMBO Practical Course is to disseminate the knowledge and proficiency in this technically challenging ribonomics method. We will guide the participants through the complete protocol, placing special emphasis on critical optimisation steps and controls. We will further discuss the bioinformatics strategies for analysis of iCLIP data. The hands-on sessions in the laboratory will be complemented by presentations by established scientists that will share their experience on using iCLIP to answer different biological questions.

Registration deadline

Sunday, 16th August 2015

Selected participants will be notified by

Friday, 4th September 2015

Apply now!

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Sponsors

 

Speakers

 

Programme

 

Registration

Registration deadline

Sunday, 16th August 2015

Selected participants will be notified by

Friday 4th September 2015

 

 

Student/postdocs

EUR400

Academic

EUR400

Industry

EUR1000

 

 

 The registration fee includes:

  • course fees,
  • course materials,
  • accommodation in single rooms,
  • excursions,
  • full catering (breakfast, lunch, dinner and refreshments).

 

Selection criteria

The course is limited to 18 participants, which will be selected according to the following criteria:

  • Participants should have experience in experimental RNA biology.
  • The course content should be relevant to their research, ie. participants should be likely to use e.g. iCLIP or a related technologies (Hits-CLIP, PAR-CLIP, ribosome profiling) as part of their project in the near future.
  • We will prioritise applications from junior researchers at the PhD and early postdoc stage.

 

Applicants are required to provide the following information:

  • a statement of motivation (max. 2000 characters including spaces)
    1. include your relevant skills, experience and qualifications which show that you would be suitable for the practical course.

    2. explain why you would like to attend, including what you can contribute and how you think you will benefit from the practical course.
  • an abstract of your current research (max. 1500 characters including spaces)
  • a concise CV

Only complete applications will be considered. Applications will be evaluated and selected by the organizers based on suitability for the course. Selected participants will be contacted by e-mail by September 4th, 2015. If positions remain open future rounds of selection will be performed, therefore you might be notified later.

Payment

Payment details will be sent to successful applicants.

 

Travel grants

A limited number of travel grants are available for eligible participants. Applicants do not need to apply separately for travel grants for this event. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants' page.

 

Contact

Mary Montemayor

IMB Events Office

Phone: +49-6131-3921451

Email: iCLIP@imb-mainz.de

 

 

 

Location & Transport

Venue

Institute of Molecular Biology (IMB)
Ackermannweg 4
55128 Mainz
https://www.imb-mainz.de/

 

View Larger Map

The city of Mainz is a charming, open-minded city. It dates back 2,000 years to Roman times and still has a historic centre with a magnificent medieval cathedral. It was also here, in 1450, that Johannes Gutenberg invented modern book printing. The city is located at the confluence of two of the most important rivers in Germany, the Rhine and the Main, and has spectacular esplanades.

Mainz is within easy reach of both cosmopolitan Frankfurt, with its famous opera house, avant-garde museums and glass-and-steel banking district, and the Rhine valley region with its castles, vineyards and nature reserves that offer great outdoor activities.

 

Accommodation

Participants and trainers will stay in single rooms at Advena Europa Hotel Mainz, for details visit here.

All guest rooms have free WiFi access.

The Advena Europa Hotel Mainz is within walking distance from the main train station.

 

TRAVEL

Arriving by plane

There are two airports near Mainz:

Frankfurt International Airport
• train (EC, ICE, IC, RE, RB) or S-Bahn (line S8) transit from Frankfurt International Airport to Mainz main station
• duration: 30-40 minutes
• ticket price: €4-8 (depending on the train)
• for schedule information see: http://www.bahn.de

Airport Frankfurt-Hahn (Hunsrück)
• bus transfer to Mainz main station: ORN from terminal 3 (leaves Frankfurt-Hahn every 3 hours)
• duration: 90 minutes
• ticket price: approx. €10
• for schedule information visit here.

Arriving by train

The best way to reach IMB from the train station is the bus line #69 (‘Campuslinie’) via the Mainz University Campus. The bus stop Duesbergweg is located in front of the IMB building. For more information visit here.