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Mitochondria, apoptosis and cancer (MAC 2015)

10 – 12 September 2015 | Frankfurt, Germany



About the workshop

Mitochondria are the cells’ powerhouse, but also their suicidal weapon store. Dozens of lethal signaling pathways converge on mitochondria to cause mitochondrial outer membrane permeabilization, leading to the cytosolic release of proapoptotic proteins and the impairment of bioenergetic functions. Furthermore, mitophagy, the specific autophagic elimination of mitochondria, represents a key regulatory mechanism of cellular homeostasis. Mitochondria-targeted drugs are considered as promising alternatives to eradicate chemotherapy-resistant cancer cells, since they directly initiate mitochondrial perturbations independently of upstream signaling events. Thus, novel insights into the control of mitochondrial functions and their deregulation in human cancers will open new perspectives to develop innovative cancer therapeutics.
The overall aim of the EMBO Workshop is to bring together, in a focused manner, world leaders in several areas of biology and medicine, focusing on mitochondria and cancer from the point of view of cell death, the most efficient way to combat cancer.
Major objectives are:

  • To gather leading scientists to discuss the most recent advances in the areas of mitochondria, apoptosis and cancer.
  • To facilitate the interaction of established leaders in the field with junior scientists.
  • To foster career development of female and young scientists.
  • To promote international scientific exchange across borders.
Mitochondria are the cells' powerhouse and exert many vital functions during normal physiology. In addition, mitochondria are centrally involved in the regulation of various modes of cell death. Mitochondria are often altered in human malignancies. Engaging mitochondria-controlled signaling pathways presents an attractive possibility to activate lethal effectors in cancer cells. Various upstream signal transduction pathways converge on mitochondria, leading to the cytosolic release of proapoptotic proteins and to the impairment of their bioenergetic functions. Activation of the cell death machinery in cancer cells by inhibiting tumor-specific alterations of the mitochondrial metabolism or by stimulating mitochondrial membrane permeabilization could therefore be promising therapeutic approaches. This workshop will build on the recent advances in the research field, bringing together world leaders as well as young talented researchers to discuss the latest results. To our best knowledge, no workshop or conference has been organized with this focus despite the actuality and the importance of the topic. Getting together experts in the field will promote further research and result not only in multiple new and fruitful international collaborations, but also in the development of efficient and selective anticancer therapeutic approaches. The EMBO Workshop will attract and promote young scientists in this field of research.

Abstract submission deadline

15 July 2015

Registration deadline

15 July 2015

Selected participants will be notified by

30 July 2015


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Join the event

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Abstract submission deadline

15 July 2015

Registration deadline

15 July 2015

Selected participants will be notified by

30 July 2015


Students/Post Doc Academic Industry

€ 300

€ 350

€ 1,000





Registration includes:

  • Lunch and coffee breaks
  • workshop material



Detailed account information will be sent by email to all selected participants upon registration.


Selection criteria

20 participants that are prominent in their research areas (relevant to the major objective of the workshop) will be selected. Additional presenters will be selected based on the quality of their submitted abstracts. Where possible preference will be given to young scientists at the beginning of their research career and a fair repesentation of gender will be taken into consideration. Selected poster authors will be asked to provide a short oral presentation.

Requested poster size: DIN A0: 841 mm width x 1189 mm height.


Travel grants

A limited number of travel grants are available for eligible participants. Applicants do not need to apply separately for travel grants for this event. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants' page.



Christina Hugenberg




venue map


University Hospital Frankfurt/Main
Campus Niederrad
Lecture Hall 22
Theodor-Stern-Kai 7, 60590 Frankfurt, Germany

The Lecture Hall 22 is located near the main entrance of the University Hospital (Building No 22).

Rooms have been reserved in three different hotels in Frankfurt as well as in a youth hostel. The hotel rooms can be booked using the keyword "EMBO Workshop 2015".


Hotel Pearl
Gutleutstr. 173, 60327 Frankfurt
Tel.: +49-69-2713669-555

IBIS Frankfurt Centrum
Speicherstr. 4, 60327 Frankfurt
Tel.: +49-69-27303153

Dorint Hotel
Hahnstr. 9, 60528 Frankfurt
Tel.: +49-69-663060

Haus der Jugend (Youth Hostel)
Deutschherrnufer 12, 60594 Frankfurt
Tel.: +49-69-6100150


Frankfurt is one of the most international cities in Germany which is very well connected to all major European cities and is a central transportation hub. The open and hospitable atmosphere in Frankfurt stems from its centuries-old role as a trading centre. This liberal and democratic tradition of the city may be one reason for the fact that people from very diverse cultures have lived here in peace with one another for a long time. Directly opposite the high-rise buildings of the financial district, on the other side of the Main, is a unique collection of 13 museums. These are devoted to different works of art, from classical paintings to modern media. In brief, the smallest metropolis in the world has interesting offers for extensive tours of the city and has cultural enjoyment awaiting you.