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Computational analysis of protein-protein interactions: From sequences to networks

28 September – 3 October 2015 | Norwich, UK

About the practical course

Recent growth in protein-protein interaction (PPI) data provides new opportunities for gaining biological insights. This EMBO Practical Course aims to train participants to use bioinformatics tools for predicting and analysing PPIs from their own datasets. The practical course will give trainees direct access to developers of several key tools, who are included amongst the trainers (Pfam, ELM, IUPRED, Cytoscape, STRING, CHIMERA).

The EMBO Practical Course will start by focussing on prediction of PPI modules from protein sequences. We will highlight differences in structure, function, and bioinformatics between globular (protein "domains") and non-globular (found in intrinsically disordered peptide regions e.g. short protein-binding regions involved in signal transduction and other biological functions) modules.

Understanding differing roles these modules can play in PPIs is key to unravelling the dynamism of cellular systems. The focus then shifts to large PPI datasets, emphasising a network perspective.

Our understanding of interactions between proteins has recently expanded greatly. In particular, we now understand much better the diversity, and importance, of interactions involving intrinsically disordered protein (IDP) regions. This has led to considerable growth in bioinformatics tools for working with IDP data. Thus, an important component of the course involves lectures on the theory and practical implications of these developments in our understanding of protein-protein interactions.

Registration deadline

15 June 2015

Selected participants will be notified by

26 June

Payment deadline

10 July 2015

Apply now!

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Registration deadline

15 June 2015

Selected participants will be notified by

26 June 2015

Payment deadline

10 July 2015


Students Academic Industry











Registration includes:

  • 7 nights’ accommodation
  • Transport to/from hotel to venue
  • All meals and refreshments for duration of the course
  • Transport for excursion
  • Course materials

Selection criteria:
We expect that delegates will be actively conducting research in a field involving some or all aspects of the material taught in the course. Thus, our selection criteria will focus on estimating the degree to which the students can use what is taught in the course, to be applied to their current research projects.
We will also look at the previous exposure students have had to bioinformatics and computational approaches to biology. We will select those most likely to understand the material presented bearing in mind that it is unlikely that students will have advanced bioinformatics experience.


Payment details will be provided by e-mail once acceptance has been confirmed.



Matt Drew

Phone: +44 1603 450264




venue map



Accommodation details:

Maids Head Hotel,

20 Tombland,


NR3 1LN,

United Kingdom

There are single occupancy rooms reserved at the hotel for all participants, which need to be confirmed 30 days prior to start on course, this is inclusive of breakfast and WiFi. Check in 27 September and check out 4 October.


Norwich 4 miles
London Stansted 84 miles
London Heathrow 140 miles
London Gatwick 150 miles

Norwich Train Station has connections from London Stansted, Gatwick and Heathrow airports.

National express services from London Stansted, Gatwick and Heathrow. Local bus services available from Norwich airport into Norwich City Centre.