Small angle neutron and X-ray scattering from proteins in solution

18 - 22 May 2015 | Grenoble, France


About the workshop

This EMBO Workshop will cover the use of small angle scattering (SAS) of both neutrons and X-rays for the determination of the structures of biological macromolecules. Particular attention will be paid on this course to sample preparation and the analysis and interpretation of SAS data in a biological context. The aim of this course is to enable the participants to maximise the information gained from the SAS technique in their future experiments.

Small angle scattering is a powerful technique for determining the structures of biological molecules in solution. Not only can small angle scattering provide precise information concerning the size, molecular weight, volume and shape of single molecules but it can also provide detailed information from large, multi-component macromolecular complexes. For these purposes the scattering properties of neutrons are particularly well suited. Through the use of specific isotope labeling techniques and solvent contrast variation it is possible to determine the structural organisation of specific components within a large macromolecular assembly.

Taking advantage of the location of the European Synchrotron Radiation Facility (ESRF) and the Institut Laue Langevin (ILL) on the same scientific campus in Grenoble, this course will focus on the complimentary use of X-ray and neutron small angle scattering for the determination of the structures of biological macromolecules. Through the use of lectures, tutorials and practicals it is intended to teach scientists new to the technique how to optimize their experiments to gain the maximum amount of information from these techniques. In particular the course will focus on:

  • Small angle scattering theory
  • Sample requirements for a successful small angle scattering experiment
  • Data analysis, model building and interpretation
  • Isotope labelling strategies for small angle neutron scattering
  • Analysing small angle scattering in conjunction with data obtained from other techniques (NMR, AUC, EM, SEC-MALLS)


Registration deadline

1 March 2015

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Registration deadline

1 March 2015




Students Academic Industry

€ 200

€ 300

€ 1000


Online application

Apply now!



Registration includes:

  • Accommodation
  • Lunch and coffee breaks



A payment link will be sent to all successful participants on 16th March.


Selection criteria

Participants will be selected on the basis of their project and their intended use of small angle scattering for that project.


The abstract must be submitted with registration and should describe the candidates’ current work, their experience using small angle scattering and their intended future experiments using small angle scattering.

Travel grants

The aim of these grants is to facilitate the participation of those coming from labs located in countries in need of scientific strengthening (whether located within Europe or internationally). Priority is given to selected participants working in the following countries: Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Malta, Poland, Portugal, Slovakia, Slovenia, Spain, Taiwan and Turkey.

These grants are designed to cover economy travel to attend the meeting. Visa costs, accommodation and subsistence will not be covered by these funds. Please contact the organisers directly for more information.


In addition to these grants there are several other grants available, please visit this page for more information.



Laurence Tellier

Phone: +33 (0)4 76 20 70 60






European Photon and Neutron Science Campus
71 avenue des Martyrs

Information concerning travel to the EPN Campus can be found here.


All participants will be housed together at the Hotel des Alpes.


venue map