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DNA topoisomerases, DNA topology and human health

13 – 17 September 2015 | Les Diablerets, Switzerland

About the workshop

The helical structure of DNA and the helical organization of chromatin fibres necessarily involve topological problems arising during vital processes like DNA replication, transcription, recombination and chromatin packing. In healthy cells all these problems are resolved by the action of nuclear enzymes DNA topoisomerases. These complex enzymes transiently cut one or two DNA strands and permit another strand or another double helix to pass through the transient break before it is religated. Since practically all DNA transactions depend (at least to some extent) on the action of DNA topoisomerases these enzymes play a central role in the proper functioning of DNA. It is very important to know the mechanisms of action of these enzymes to better understand functioning both of healthy cells and of cancer cells. For example, DNA topoisomerase inhibitors constitute one important class of anti-cancer drugs. In addition to scientists working on DNA topoisomerases, our EMBO Workshop will also group together scientists studying topological problems arising during DNA replication, transcription and recombination or chromosome segregation. Our objective is to contribute to the growth of knowledge in the field of DNA topology by bringing together leaders in the field with the new generation of young scientists from many European countries.


This EMBO Workshop is supported by SKMB.


Registration and abstract submission deadline

1 August 2015

Accepted participants will be notified by

30 June 2015

Payment deadline

31 July 2015

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Registration and abstract submission deadline

31 May 2015

Selected participants will be notified by

30 June 2015

Payment deadline

31 July 2015










Registration includes:

  • refreshments at the meeting



Payment details will be sent by email to successful applicants.



Accommodation is NOT included. After the selection process, accepted participants should fill in the Hotel booking form (pdf) and, either, fax (+41 24 492 2371) or email ( back the form for confirmation.

The hotel must be booked by 15 August 2015.



Accepted participants must pay the hotel directly for their accommodation at the conference package rate.


Accommodation details:


CHF 245.- per night and per person in a single room

CHF 190.- per night and per person in a double room


These rates include:

  • Overnight
  • Welcome drink on arrival day
  • Breakfast-buffet
  • Lunch with 3 courses (drinks not included)
  • Dinner with 4 courses (drinks not included)
  • Mineral water during the conference
  • Free use of our salle Diablerets in “theatre style”, (no tables, only chairs) for 120 persons including a screen, a beamer and flipcharts
  • 2 coffee breaks per day
  • Free entrance in our indoor swimming pool and in our sauna and sanarium
  • Taxes, service and VAT
  • Free Wi-Fi at the hotel
  • Free access card


Selection criteria

Scientific and geographic broad distribution. In the event of the workshop being oversubscribed the date of application will be used as a selection criteria.




Caroline Austin




venue map


Eurotel Victoria

Chemin du Vernex, 1865 Les Diablerets, Switzerland
http: //

Tel : +41 (0) 24 492 37 21
Fax : +41 (0) 24 492 23 71



The closest international airport is Genève Aéroport.

From Geneva Airport:

Go to the train station (CFF-SBB) in the airport, buy a train ticket to Les Diablerets. Train tickets can be bought at the counter or using machines in the train station, but can be bought online (first or second class tickets, as well as bargain tickets).


Every hour there is a train from Geneva Airport to Les Diablerets with one change in Aigle: check the train schedule. You need to take the "Aigle–Sépey–Diablerets " train. The journey takes 2 hours and 20 minutes. The first 1.5 hour is on a fast train to Aigle,once there you will have to change to a mountain railway train that will bring you to Les Diablerets (the final station).

If you arrive at Zurich airport you will need to change the train several times, it will take approximately 4 hours with the same connectinos as above: check the train schedule.

If you travel by train from Switzerland or from abroad please check the train schedule.

From the final station of the mountain railway there is only a short walk to the hotel. If you inform the hotel that you are arriving they will send a minibus, please e-mail:  Tel : +41 (0)24 492 37 21.


For car journey check the google maplink.