About the workshop
The piRNA pathway, an RNA-silencing pathway involving small non-coding RNAs and the PIWI proteins -specific Argonaute proteins- has been discovered a few years ago as a defense mechanism against transposable elements. The field is progressing rapidly and a growing number of studies have implicated piRNAs and PIWI proteins in a broad range of functions, including gene and epigenetic regulation, genome rearrangements and stem cell biology. The questions linked to piRNA functions are thus widely expanding. This EMBO Workshop aims to provide a forum to discuss and connect the most recent advances in the different functions of piRNAs and PIWI proteins.
We will address piRNA biogenesis and the role of piRNAs/PIWI proteins in genome defense; epigenetic regulation; stem cell biology; post-transcriptional gene regulation; somatic tissues and cancer; and genome rearrangements.