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Computational analysis of protein-protein interactions: Sequences, networks and diseases

30th May - 4th June 2016 | Budapest, Hungary

Registration deadline

15 February 2016

Selected participants will be notified by

01 March 2016

Payment deadline

24 March 2016

Apply now!

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About the practical course

Recent growth in protein-protein interaction (PPI) data provides new opportunities for gaining insights into biological systems. A major focus of this EMBO Practical Course will be teaching the importance of PPIs in these systems, and how bioinformatics tools can be harnessed for understanding and controlling physiological states and when these states are perturbed by disease.
 
Ideal participants for this course are bench scientist who are working to obtain data related to protein-protein interactions, or already have such data they are working to analyse. This might include 3D protein structural data, results from low- or high-throughput PPI detection methods (yeast-two-hybrid, TAP-tagged pulldowns, etc.), datasets for building biological networks that could be relevant for inferring PPIs (e.g. gene expression data) or predicting potential interaction partners for proteins or systems of interest.
 
This EMBO Practical Course aims to train participants to use bioinformatics tools for predicting and analysing PPIs from their own datasets. Without these skills, bench scientists risk missing important insights from such data. Another aim is to give trainees direct access to trainers who are developers of key tools (Pfam, ELM, IUPRED, Cytoscape, STRING, CHIMERA).
 
The content of the course will be similar to that of an EMBO Practical Course taught in Norwich in September 2015. These pages contain all the material taught during the course, you may find it useful to look at this when deciding whether to apply for the course.
 
We initially focus on predicting PPI modules from protein sequences, highlighting differences (structure, function, and bioinformatics) between globular protein "domains" and non-globular intrinsically-disordered peptide regions, the latter being rich in short protein-binding regions involved in signal transduction and other functions. Understanding the differing roles these modules play in PPIs is key to unraveling the dynamism and complexity of cellular systems. The EMBO Practical Course ends by focusing on large PPI datasets, emphasizing a network perspective.
 
The final version of the course program, with links to all the training material, can be found on these pages hosted by github.

 

Speakers

 

Programme

The final version of the course program, with links to all the training material, can be found on these pages hosted by github.

 

 

Registration

Registration deadline

15 February 2016

Selected participants will be notified by

01 March 2016

Payment deadline

24 March 2016

 

Local

EUR100

Student/postdocs

EUR200

Academic

EUR400

Industry

EUR1000

 

 

 

 

Registration includes:

  • Accomodation (7 nights)
  • Course materials
  • Meals, coffee breaks
  • Social events, excursion
  • Budapest card for public transportation
    Note: Local registration does not include accommodation.

Selection Criteria

We expect that students will be actively conducting bench research in a field involving some or all aspects of the material taught in the course. Ideally they will already have data they are interested in analysing to bring along to the course. Thus, our selection criteria will focus on estimating the degree to which the students can use what is taught in the course, to be applied to their current research projects.

 

We will also look at the previous exposure students have had to bioinformatics and computational approaches to biology. We will select those most likely to understand the material presented, bearing in mind that it is unlikely that students will have advanced bioinformatics experience.

Payment

Payment instructions will be sent to successful applicants once the selection procedure is complete.

Poster Specifications

We expect all course participants to present a poster (A0 size portrait format) describing their project at the course.

Additional Information

There will be single occupancy hotel accommodation for trainers and double rooms for trainees in the same hotel which is conveniently located near the venue.

Payment

Selected candidates will be sent payment information by email.

Travel Grants

There are 4 travel grants funded by EMBO and 10 by the COST NGP action. EMBO travel grants are available for attendees working in the following countries: Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Malta, Poland, Portugal, Slovakia, Slovenia, Spain, Taiwan and Turkey.

COST travel grants are available for attendees working in the following countries:
Austria, Belgium, Croatia, Cyprus, Czech Republic, Denmark, Finland, France, Germany, Greece, Ireland, Israel, Italy, Latvia, Lithuania, Norway, Poland, Portugal, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, United Kingdom and for attendees working in the Institute of Protein Research in the Russian Federation.


Please indicate your interest for an EMBO Travel Grant during registration.

 

 

 

Contact

Tamás Szaniszló
Email: embo2016bp@ttk.elte.hu

 

 
venue map

Venue

Pázmány Péter sétány 1/C
H-1117 Budapest
Hungary
Website

Accommodation

Hotel Danubius "Flamenco"
Tas vezér utca 3-7
H-1113
Budapest
Hungary
Website

 

Trainees will share twin rooms in the Danubius Flamenco Hotel. The hotel is about 20 minutes walking distance from the venue. The venue can be reached on several city buses (number 154 or 153) and there is a tram stop about 10 minutes walk from hotel (number 4 or number 6). The hotel is set in green surroundings with wellness facilities and car parking areas. Hotel rooms will be booked by the organisers.

Travel

Budapest, as the capital of Hungary, is the major transport hub of the country. It can easily be reached by plane from the majority of the world. The Liszt Ferenc airport is about 20 kilometers from the venue. For those who choose air transport, the organisers will provide transfer from the airport, which is inlcuded in the registration fee. From neighbouring countries, the city can be reached by railways and is also well connencted by highways.

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